Chemicals may help restore lost vision in blind man
Chemicals in some of the drugs sold to people with macular degeneration may help sight in people who lost vision during their illness, a new study finds.
The findings are a reminder of the critical importance of taking eye care with an eye doctor and the importance of maintaining good vision, said Dr. William Schofield, director of the MRC Eye Institute at King’s College London.
A study of eye care products sold by a leading U.K. drugstore chain showed that products containing carbamazepine, a type of anticoagulant used to treat diabetes, reduced the risk of developing macular cancer.
The products also reduced the chance of developing retinal detachment, or damage to the retina that occurs when an eye falls off.
The researchers looked at eye care treatments marketed to people aged 65 or older and compared them with a group of products marketed to younger people.
The research was published today (Aug. 28) in the journal Lancet.
“We are now aware that the macular progression in people with the disease is not as well controlled as in people without the disease,” Schofild said.
“Our data is consistent with the view that the combination of a number of macular health problems, including diabetes, could lead to retinal degeneration in people over 65.”
This is especially true if they have had some type of retinal loss before the age of 65.
“For the study, researchers compared eye care formulations marketed by three British drugstore chains to the same products marketed by a third chain, which also had a large number of eye products marketed under different brand names.
The researchers looked for differences in the eye products, including the ingredient list, the dosage, and the packaging.
The drugstore brands sold under the brand names Sisene, Janssen and Stryker were the same as those marketed by the third chain.
The results were similar to those from a recent study in the New England Journal of Medicine that found a small but significant reduction in the risk for developing macula, or the scar that forms on the retina when the eye falls out.
That study, conducted in 2012, showed that using the same drugstore formulation that had been used to lower risk of macula in people older than 65 was associated with a 15% reduction in risk of progression to the stage of clinical disease.
But the study did not look at macular decline among people younger than 65.
This study looked at the effect of a different formulation, a newer formulation that does not appear to reduce macular risk.”
Our findings indicate that using a different brand formulation of maculopathy drug could have a significant impact on macular disease progression,” said Schofould, a professor of dermatology at the University of Cambridge.
Schofield and colleagues at King and Imperial College London examined drugstore formulations that were marketed to the British public.
They looked at three drugs for macular maculopathies, namely carbamazetine, the main anticoage agent used to prevent and treat diabetes.
The drugs were marketed under the generic name Sisine, Jannsen and the Strykers brand.
They were not sold in the U.S. or other countries, and there was no specific information on the ingredients in the drugs.
The study showed that, overall, the macula drug was associated less with macula progression in older people than with maculoma progression in younger people and a small, nonsignificant reduction in macula risk among older people compared with younger people, the researchers wrote.
However, the authors also found that maculos were associated with increased risk of both macula and macular non-progressiveness among older adults, although the difference was not statistically significant.
The authors also analyzed a drugstore brand for a possible explanation for the differences in macular rates between the drugstores and the generic brands.”
The differences in rates of macules may be due to differences in how often the drugs are taken, whether they are used alone or with other drugs, or whether the drugs have different active ingredients or have different dosage forms,” they wrote.
In addition, they noted that some of these drugs have been associated with higher rates of adverse reactions.
The makers of the drugstore drugs did not immediately respond to requests for comment.